Drug Name:Sodium Oxybate
Drug Class:Central Nervous System Depressant
Mechanism of Action:
  • Acts on GABA-B receptors to increase slow wave sleep
  • Reduces cataplexy and excessive daytime sleepiness
Use:
  • Treatment of narcolepsy with cataplexy
  • Reduction of excessive daytime sleepiness
Side Effects:
  • Nausea
  • Vomiting
  • Dizziness
  • Headache
  • Sweating
  • Tremors
  • Confusion
  • Depression
  • Suicidal thoughts
Contraindications:
  • Hypersensitivity to sodium oxybate
  • History of addiction or abuse of alcohol or drugs
  • Severe respiratory depression
  • Severe liver or kidney disease
  • Use of other CNS depressants
Specialty:
  • Neurology
  • Sleep Medicine